Basics in molecular biology and biotechnology

The main goal of the “Introductory Course”, is to provide one-week extensive initial training to First-year PhD
students, to provide them basic background knowledge, at the beginning of the academic year, necessary to be introduced the various fields of research.
Different group leaders provide to students a presentation of their research activities and projects and students will be also introduced to research facilities
running at UNG and ICGEB.

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• Background introductory lectures related to UNG and ICGEB research activities in the following topics: DNA replication, recombination and repair, RNA processing and micro RNA
metabolism, regulation of gene expression, dynamic organization of nuclear structure and function, protein synthesis and interactions, protein structure, cell cycle and cancer, human
molecular genetics, animal models of human disease, molecular genetics of yeast, molecular genetics of Drosophila, molecular genetics of bacteria, human virology and oncogenesis,
molecular and cellular immunology, stem cells and differentiation of stem cells, recombinant binders and their application, yeast ecology and application, bioinformatics.
• Tutorials in informatics, proteomics, microscopy, flow cytometry, analytical methods, safety procedures.
• Presentation of group leaders and presentation
of research projects
• Presentation of institutional technical facilities

• Students learn basic background knowledge of molecular biology and biotechnology.
• Students are introduced to technical facilities at ICGEB and UNG.
• Students meet scientists, researchers and all scientific community and learn research interests at ICGEB and UNG.

• G. Alberts, Johnson, Lewis, Morgan, Raff, Roberts, Walter: Molecular Biology of the Cell, 6th Ed., W. W. Norton & Company, 2014. Catalogue E-version
• Alberts B. et al.: Essential Cell Biology. 2016, Fourth Edition. W.W. Norton. Catalogue E-version
• Benjamin Lewin, GENES IX, © Copyright 2014 Jones and Bartlett Publishers. E-version
• Nature Reviews in Cell Biology. E-version
• Nature Reviews in Genetics. E-version
• Literature relevant for the course.

Questionnaire 100%

Asst. prof. dr. Lovšin is a research associate at the Department of Clinical Biochemistry of the Faculty of Pharmacy,
University of Ljubljana. Her research interests include APOBEC antiviral proteins, nanoparticle toxicity studies, and the
study of gene function in various diseases. She received her postdoctoral training at UCSF in the USA and the Weizmann
Institute in Israel.

• Lovšin, Nika; Gangupam, Bhavani ; Bergant Marušič, Martina. The intricate interplay between APOBEC3 proteins and
  DNA tumour viruses. Pathogens. 2024 ISSN 2076-0817. - Vol. 13, no. 3, art. 187, 19 str.
• Malavašič, Petra ; Polajžer, Sara ; Lovšin, Nika. Anaphase-promoting complex subunit 1 associates with bone mineral
  density in human osteoporotic bone. 2023. International journal of molecular sciences ISSN 1422-0067. - Vol. 24, no.
  16, art. 12895, 16 str.
• KODRIČ, Klemen, ZUPAN, Janja, KRANJC, Tilen, KOMADINA, Radko, MLAKAR, Vid, MARC, Janja, LOVŠIN, Nika. Sex-
  determining region Y (SRY) attributes to gender differences in RANKL expression and incidence of osteoporosis.
• Experimental and molecular medicine. Aug. 2019, vol. 51, no. 8, str. 1-16, ilustr. ISSN 2092-6413.
  Kovač Viršek, Manca ; Lovšin, Nika ; Koren Bačovnik, Špela; Kržan, Andrej ; Peterlin, Monika. Microplastics as a vector
  for the transport of the bacterial fish pathogen species Aeromonas salmonicida. Marine pollution bulletin.2017, ISSN
  0025-326X. - Vol. 125, iss. 1/2, str. 301-309
• LINDIČ, Nataša, BUDIČ, Maruška, PETAN, Toni, KNISBACHER, Binyamin A., LEVANON, Erez Y., LOVŠIN, Nika.
  Differential inhibition of LINE1 and LINE2 retrotransposition by vertebrate AID/APOBEC proteins. Retrovirology, 2013
  ISSN 1742-4690. Online ed.
• OKEOMA, Chioma M., LOVŠIN, Nika, PETERLIN, Matija Boris, MARKI, Susan Ross. APOBEC3 inhibits mouse mammary
  tumour virus replication in vivo. Nature : the international weekly journal of science, ISSN 0028-0836. [Print ed.],
  2007, vol. 445, no. 7130, str. 927-930