Plant bioactive compunds

• Survey of some plant bioactive compounds, emphasizing on polyphenols in fruit. Presentation of bioavailability (absorption and target organs) of some representative polyphenols
• Molecular basis of cellular actions of plant bioacitve compounds
• Description of different approaches in the analysis of plant bioactive compounds: targeted approach, non-targeted approach - metabolomics, and fluxomics – analysis of fluxes. Analytical technologies applied in these fields of research and their applications

Chemical analyses of grapes/must/wine

• Physical-chemical properties of plant biactive compounds, their technological meaning and their biovailability in mammals.
• Molecular basis of cellular actions of plant bioacitve compounds.
• Metabolomics of plant bioactive compounds.

Obtained knowledge and understanding: * Understanding of physical-chemical properties of plant bioactive compounds, their bioavailability burdens and their potential bioactivity. * Knowing of basic analytical approaches in determination of bioactive compounds in plants or in animal tissues: sample preparation (extraction and cleaning), analytical tools for liquid and gas chromatography (HPLC, GC) with different detectors.

• Flavonoids: Chemistry, Biochemistry and Applications. 2006. Q.M. Andersen and K.R. Markham, Editors, CRC Press; Taylor & Francis, Boca Raton: 1197 str. Catalogue
• Macheix J.J., Fleuriet A., Billot J. 1990. Fruit phenolics. Boca Raton, CRC Press: 378 p.
• Hames D.; Hooper N. Instant Notes Biochemistry. 2005, Taylor & Francis Group: 438 str. E-version
• Patrick G. Instant Notes Medicinal Chemistry. 2001. Taylor & Francis Group: 278 str. E-version
• McLaughlin D., Stamford J., White D. Instant Notes Human Physiology. 2007. Taylor&Francis Group: 460 str. E-version
• Biotechnology in agricultural and forestry: 57. Plant metabolomics, edited by Saito K., Dixion R.A., Willmitzer L. E-version

Seminar is obligatory to participate (30%) and written examination (70%)

Associate professor in the field of Food technology.

References of the professor .